Erythroid Cells Rendered Erythropoietin Independent by Infection with Friend Spleen Focus-Forming Virus Show Constitutive Activation of Phosphatidylinositol 3-Kinase and Akt Kinase: Involvement of Insulin Receptor Substrate-Related Adapter Proteins

The erythroleukemia-inducing Friend spleen focus-forming virus (SFFV) encodes a unique envelope glycoprotein which allows erythroid cells to proliferate and differentiate in the absence of erythropoietin (Epo). In an effort to understand how SFFV causes Epo independence, we have been examining eryth...

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Bibliografski detalji

Izdano u:	J Virol
Glavni autori:	Nishigaki, Kazuo, Hanson, Charlotte, Ohashi, Takashi, Thompson, Delores, Muszynski, Karen, Ruscetti, Sandra
Format:	Artigo
Jezik:	Inglês
Izdano:	American Society for Microbiology (ASM) 2000
Teme:	Pathogenesis and Immunity
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111802/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10708418/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.7.3037-3045.2000
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