Erythroid Cells Rendered Erythropoietin Independent by Infection with Friend Spleen Focus-Forming Virus Show Constitutive Activation of Phosphatidylinositol 3-Kinase and Akt Kinase: Involvement of Insulin Receptor Substrate-Related Adapter Proteins

The erythroleukemia-inducing Friend spleen focus-forming virus (SFFV) encodes a unique envelope glycoprotein which allows erythroid cells to proliferate and differentiate in the absence of erythropoietin (Epo). In an effort to understand how SFFV causes Epo independence, we have been examining eryth...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Nishigaki, Kazuo, Hanson, Charlotte, Ohashi, Takashi, Thompson, Delores, Muszynski, Karen, Ruscetti, Sandra
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111802/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10708418/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.7.3037-3045.2000
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