Erythroid Cells Rendered Erythropoietin Independent by Infection with Friend Spleen Focus-Forming Virus Show Constitutive Activation of Phosphatidylinositol 3-Kinase and Akt Kinase: Involvement of Insulin Receptor Substrate-Related Adapter Proteins

The erythroleukemia-inducing Friend spleen focus-forming virus (SFFV) encodes a unique envelope glycoprotein which allows erythroid cells to proliferate and differentiate in the absence of erythropoietin (Epo). In an effort to understand how SFFV causes Epo independence, we have been examining eryth...

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הוצא לאור ב:	J Virol
Principais autores:	Nishigaki, Kazuo, Hanson, Charlotte, Ohashi, Takashi, Thompson, Delores, Muszynski, Karen, Ruscetti, Sandra
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2000
נושאים:	Pathogenesis and Immunity
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111802/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10708418/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.7.3037-3045.2000
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