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The c-myc Locus Is a Common Integration Site in Type B Retrovirus-Induced T-Cell Lymphomas

Type B leukemogenic virus (TBLV) induces rapidly appearing T-cell leukemias. TBLV insertions near the c-myc gene were detectable in 2 of 30 tumors tested, whereas 80% of the tumors showed c-myc overexpression. TBLV insertions on chromosome 15 (including a newly identified locus, Pad7) may cause c-my...

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Podrobná bibliografie
Vydáno v:J Virol
Hlavní autoři: Rajan, Lakshmi, Broussard, Dana, Lozano, Mary, Lee, Chun G., Kozak, Christine A., Dudley, Jaquelin P.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111733/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10666282/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.5.2466-2471.2000
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