The c-myc Locus Is a Common Integration Site in Type B Retrovirus-Induced T-Cell Lymphomas

Type B leukemogenic virus (TBLV) induces rapidly appearing T-cell leukemias. TBLV insertions near the c-myc gene were detectable in 2 of 30 tumors tested, whereas 80% of the tumors showed c-myc overexpression. TBLV insertions on chromosome 15 (including a newly identified locus, Pad7) may cause c-my...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Rajan, Lakshmi, Broussard, Dana, Lozano, Mary, Lee, Chun G., Kozak, Christine A., Dudley, Jaquelin P.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 2000
Assuntos:	Transformation and Oncogenesis
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111733/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10666282/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.5.2466-2471.2000
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