The c-myc Locus Is a Common Integration Site in Type B Retrovirus-Induced T-Cell Lymphomas

Type B leukemogenic virus (TBLV) induces rapidly appearing T-cell leukemias. TBLV insertions near the c-myc gene were detectable in 2 of 30 tumors tested, whereas 80% of the tumors showed c-myc overexpression. TBLV insertions on chromosome 15 (including a newly identified locus, Pad7) may cause c-my...

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Detaylı Bibliyografya
Asıl Yazarlar: Rajan, Lakshmi, Broussard, Dana, Lozano, Mary, Lee, Chun G., Kozak, Christine A., Dudley, Jaquelin P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 2000
Konular:
Transformation and Oncogenesis
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC111733/
https://ncbi.nlm.nih.gov/pubmed/10666282
Etiketler: Etiketle
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