Assembly of Spikes into Coronavirus Particles Is Mediated by the Carboxy-Terminal Domain of the Spike Protein

The type I glycoprotein S of coronavirus, trimers of which constitute the typical viral spikes, is assembled into virions through noncovalent interactions with the M protein. Here we demonstrate that incorporation is mediated by the short carboxy-terminal segment comprising the transmembrane and end...

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Hlavní autoři: Godeke, Gert-Jan, de Haan, Cornelis A. M., Rossen, John W. A., Vennema, Harry, Rottier, Peter J. M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2000
Témata:
Structure and Assembly
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC111495/
https://ncbi.nlm.nih.gov/pubmed/10627571
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