Assembly of Spikes into Coronavirus Particles Is Mediated by the Carboxy-Terminal Domain of the Spike Protein

The type I glycoprotein S of coronavirus, trimers of which constitute the typical viral spikes, is assembled into virions through noncovalent interactions with the M protein. Here we demonstrate that incorporation is mediated by the short carboxy-terminal segment comprising the transmembrane and end...

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הוצא לאור ב:	J Virol
Principais autores:	Godeke, Gert-Jan, de Haan, Cornelis A. M., Rossen, John W. A., Vennema, Harry, Rottier, Peter J. M.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	American Society for Microbiology (ASM) 2000
נושאים:	Structure and Assembly
גישה מקוונת:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC111495/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10627571/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.74.3.1566-1571.2000
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