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Combining Anthrax Vaccine and Therapy: a Dominant-Negative Inhibitor of Anthrax Toxin Is Also a Potent and Safe Immunogen for Vaccines
Anthrax is caused by the unimpeded growth of Bacillus anthracis in the host and the secretion of toxins. The currently available vaccine is based on protective antigen (PA), a central component of anthrax toxin. Vaccination with PA raises no direct immune response against the bacilli and, being a na...
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| Huvudupphovsmän: | , , , , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Microbiology
2005
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1111877/ https://ncbi.nlm.nih.gov/pubmed/15908368 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.73.6.3408-3414.2005 |
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