Coreceptor Competition for Association with CD4 May Change the Susceptibility of Human Cells to Infection with T-Tropic and Macrophagetropic Isolates of Human Immunodeficiency Virus Type 1

The chemokine receptors CCR5 and CXCR4 were found to function in vivo as the principal coreceptors for M-tropic and T-tropic human immunodeficiency virus (HIV) strains, respectively. Since many primary cells express multiple chemokine receptors, it was important to determine if the efficiency of vir...

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Bibliografiska uppgifter
Huvudupphovsmän: Lee, Shirley, Lapham, Cheryl K., Chen, Hong, King, Lisa, Manischewitz, Jody, Romantseva, Tatiana, Mostowski, Howard, Stantchev, Tzanko S., Broder, Christopher C., Golding, Hana
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2000
Ämnen:
Virus-Cell Interactions
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC110853/
https://ncbi.nlm.nih.gov/pubmed/10799575
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