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Evidence for Common Structural Determinants of Human Immunodeficiency Virus Type 1 Coreceptor Activity Provided through Functional Analysis of CCR5/CXCR4 Chimeric Coreceptors

Human immunodeficiency virus type 1 (HIV-1) infection in vivo is dependent upon the interaction of the viral envelope glycoprotein gp120 with CC chemokine receptor 5 (CCR5) or CXC chemokine receptor 4 (CXCR4). To study the determinants of the gp120-coreceptor association, we generated a set of chime...

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Detalhes bibliográficos
Main Authors: Pontow, Suzanne, Ratner, Lee
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114737/
https://ncbi.nlm.nih.gov/pubmed/11689632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.23.11503-11514.2001
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