Cloning of a Mammalian Transcriptional Activator That Binds Unmethylated CpG Motifs and Shares a CXXC Domain with DNA Methyltransferase, Human Trithorax, and Methyl-CpG Binding Domain Protein 1

Ligand screening was utilized to isolate a human cDNA that encodes a novel CpG binding protein, human CpG binding protein (hCGBP). This factor contains three cysteine-rich domains, two of which exhibit homology to the plant homeodomain finger domain. A third cysteine-rich domain conforms to the CXXC...

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Bibliographic Details
Main Authors: Shin Voo, Kui, Carlone, Diana L., Jacobsen, Britta M., Flodin, Anna, Skalnik, David G.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2000
Subjects:
Transcriptional Regulation
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC110827/
https://ncbi.nlm.nih.gov/pubmed/10688657
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