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Cloning of a Mammalian Transcriptional Activator That Binds Unmethylated CpG Motifs and Shares a CXXC Domain with DNA Methyltransferase, Human Trithorax, and Methyl-CpG Binding Domain Protein 1

Ligand screening was utilized to isolate a human cDNA that encodes a novel CpG binding protein, human CpG binding protein (hCGBP). This factor contains three cysteine-rich domains, two of which exhibit homology to the plant homeodomain finger domain. A third cysteine-rich domain conforms to the CXXC...

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Udgivet i:Mol Cell Biol
Principais autores: Shin Voo, Kui, Carlone, Diana L., Jacobsen, Britta M., Flodin, Anna, Skalnik, David G.
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2000
Fag:
Transcriptional Regulation
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110827/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10688657/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.20.6.2108-2121.2000
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