Structure of HAP1-PC7 bound to DNA: implications for DNA recognition and allosteric effects of DNA-binding on transcriptional activation
HAP1 is a transcription factor in yeast whose DNA-binding domain has been implicated in directly affecting transcriptional activation. Two separate mutations in the DNA-binding domain, S63G (HAP1-PC7) and S63R (HAP1-18), retain wild-type binding affinity. However, HAP1-PC7 is transcriptionally silen...
I tiakina i:
| I whakaputaina i: | Nucleic Acids Res |
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| Ngā kaituhi matua: | , , |
| Hōputu: | Artigo |
| Reo: | Inglês |
| I whakaputaina: |
Oxford University Press
2000
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| Ngā marau: | |
| Urunga tuihono: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110793/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11024163/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.20.3853 |
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