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Role of FXR and FTF in bile acid-mediated suppression of cholesterol 7α-hydroxylase transcription
Bile acid biosynthesis is subjected to feedback regulation whereby bile acids down-regulate their own synthesis. The major point of this regulation is at the level of cholesterol 7α-hydroxylase (7α-hydroxylase), which controls bile acid output from the classic pathway. This regulation is at the leve...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2000
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC110735/ https://ncbi.nlm.nih.gov/pubmed/10982880 |
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