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Cholesterol and bile acids regulate cholesterol 7 alpha-hydroxylase expression at the transcriptional level in culture and in transgenic mice.

Cholesterol 7 alpha-hydroxylase (7 alpha-hydroxylase) is the rate-limiting enzyme in bile acid biosynthesis. It is subject to a feedback control, whereby high levels of bile acids suppress its activity, and cholesterol exerts a positive control. It has been suggested that posttranscriptional control...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Ramirez, M I, Karaoglu, D, Haro, D, Barillas, C, Bashirzadeh, R, Gil, G
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC358646/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8139578/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/mcb.14.4.2809
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