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Role of FXR and FTF in bile acid-mediated suppression of cholesterol 7α-hydroxylase transcription

Bile acid biosynthesis is subjected to feedback regulation whereby bile acids down-regulate their own synthesis. The major point of this regulation is at the level of cholesterol 7α-hydroxylase (7α-hydroxylase), which controls bile acid output from the classic pathway. This regulation is at the leve...

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Autores principales: del Castillo-Olivares, Antonio, Gil, Gregorio
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2000
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC110735/
https://ncbi.nlm.nih.gov/pubmed/10982880
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