Transcriptional repression of BRCA1 by aberrant cytosine methylation, histone hypoacetylation and chromatin condensation of the BRCA1 promoter

BRCA1 expression is repressed by aberrant cytosine methylation in sporadic breast cancer. We hypothesized that aberrant cytosine methylation of the BRCA1 promoter was associated with the transcriptionally repressive effects of histone hypoacetylation and chromatin condensation. To address this quest...

Cijeli opis

Bibliografski detalji

Izdano u:	Nucleic Acids Res
Glavni autori:	Rice, Judd C., Futscher, Bernard W.
Format:	Artigo
Jezik:	Inglês
Izdano:	Oxford University Press 2000
Teme:	Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110706/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10954590/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.17.3233
Oznake:	Dodaj oznaku Bez oznaka, Budi prvi tko označuje ovaj zapis!