Transcriptional repression of BRCA1 by aberrant cytosine methylation, histone hypoacetylation and chromatin condensation of the BRCA1 promoter

BRCA1 expression is repressed by aberrant cytosine methylation in sporadic breast cancer. We hypothesized that aberrant cytosine methylation of the BRCA1 promoter was associated with the transcriptionally repressive effects of histone hypoacetylation and chromatin condensation. To address this quest...

Täydet tiedot

Bibliografiset tiedot

Julkaisussa:	Nucleic Acids Res
Päätekijät:	Rice, Judd C., Futscher, Bernard W.
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Oxford University Press 2000
Aiheet:	Article
Linkit:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110706/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10954590/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/28.17.3233
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