Selenium Deficiency Reduces the Abundance of mRNA for Se-Dependent Glutathione Peroxidase 1 by a UGA-Dependent Mechanism Likely To Be Nonsense Codon-Mediated Decay of Cytoplasmic mRNA

The mammalian mRNA for selenium-dependent glutathione peroxidase 1 (Se-GPx1) contains a UGA codon that is recognized as a codon for the nonstandard amino acid selenocysteine (Sec). Inadequate concentrations of selenium (Se) result in a decrease in Se-GPx1 mRNA abundance by an uncharacterized mechani...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Moriarty, Patrick M., Reddy, C. Channa, Maquat, Lynne E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 1998
Gaiak:
Gene Expression
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC110672/
https://ncbi.nlm.nih.gov/pubmed/9566912
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