Dimerization by Translation Initiation Factor 2 Kinase GCN2 Is Mediated by Interactions in the C-Terminal Ribosome-Binding Region and the Protein Kinase Domain

Ítems similars

• Activation of GCN2 kinase by ribosome stalling links translation elongation with translation initiation
  per: Ishimura, Ryuta, et al.
  Publicat: (2016)
• The tRNA-binding moiety in GCN2 contains a dimerization domain that interacts with the kinase domain and is required for tRNA binding and kinase activation
  per: Qiu, Hongfang, et al.
  Publicat: (2001)
• Defects in tRNA Processing and Nuclear Export Induce GCN4 Translation Independently of Phosphorylation of the α Subunit of Eukaryotic Translation Initiation Factor 2
  per: Qiu, Hongfang, et al.
  Publicat: (2000)
• Evidence that GCN1 and GCN20, translational regulators of GCN4, function on elongating ribosomes in activation of eIF2alpha kinase GCN2.
  per: Marton, M J, et al.
  Publicat: (1997)
• Autophosphorylation in the Activation Loop Is Required for Full Kinase Activity In Vivo of Human and Yeast Eukaryotic Initiation Factor 2α Kinases PKR and GCN2
  per: Romano, Patrick R., et al.
  Publicat: (1998)