Targeted Recombination within the Spike Gene of Murine Coronavirus Mouse Hepatitis Virus-A59: Q159 Is a Determinant of Hepatotropism

Previous studies of a group of mutants of the murine coronavirus mouse hepatitis virus (MHV)-A59, isolated from persistently infected glial cells, have shown a strong correlation between a Q159L amino acid substitution in the S1 subunit of the spike gene and a loss in the ability to induce hepatitis...

ver descrição completa

Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Leparc-Goffart, Isabelle, Hingley, Susan T., Chua, Ming Ming, Phillips, Joanna, Lavi, Ehud, Weiss, Susan R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Viral Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110472/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9811696/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.12.9628-9636.1998
Tags:	Adicionar Tag Sem tags, seja o primeiro a adicionar uma tag!