Inhibition of Human Immunodeficiency Virus Type 1 Virion Entry by Dominant-Negative Hck

To study the role of Src family tyrosine kinases in infection with human immunodeficiency virus type 1 (HIV-1), we constructed an Hck mutant, HckN, that hinders signaling from wild-type Hck. HIV-1 produced in HckN-expressing cells was significantly less infectious to HeLa–CD4–LTR–β-gal (MAGI) cells...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Tokunaga, Kenzo, Kiyokawa, Etsuko, Nakaya, Mie, Otsuka, Naomi, Kojima, Asato, Kurata, Takeshi, Matsuda, Michiyuki
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Viral Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110455/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9621101/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.7.6257-6259.1998
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