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Chimaerin suppresses Rac1 activation at the apical membrane to maintain the cyst structure.

Epithelial organs are made of a well-polarized monolayer of epithelial cells, and their morphology is maintained strictly for their proper functions. Previously, we showed that Rac1 activation is suppressed at the apical membrane in the mature organoid, and that such spatially biased Rac1 activity i...

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Opis bibliograficzny
Główni autorzy: Shunsuke Yagi, Michiyuki Matsuda, Etsuko Kiyokawa
Format: Artigo
Język:Inglês
Wydane: Public Library of Science (PLoS) 2012-01-01
Seria:PLoS ONE
Dostęp online:http://europepmc.org/articles/PMC3527519?pdf=render
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