Papillomavirus Assembly Requires Trimerization of the Major Capsid Protein by Disulfides between Two Highly Conserved Cysteines

We have used viruslike particles (VLPs) of human papillomaviruses to study the structure and assembly of the viral capsid. We demonstrate that mutation of either of two highly conserved cysteines of the major capsid protein L1 to serine completely prevents the assembly of VLPs but not of capsomers,...

Descrizione completa

Dettagli Bibliografici

Pubblicato in:	J Virol
Autori principali:	Sapp, Martin, Fligge, Claudia, Petzak, Ingrid, Harris, J. Robin, Streeck, Rolf E.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Animal Viruses
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110432/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9621087/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.7.6186-6189.1998
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!