Infection with Cytotoxic T-Lymphocyte Escape Mutants Results in Increased Mortality and Growth Retardation in Mice Infected with a Neurotropic Coronavirus
C57BL/6 mice infected with mouse hepatitis virus strain JHM (MHV-JHM) develop a chronic demyelinating encephalomyelitis several weeks after inoculation. Previously, we showed that mutations in the immunodominant CD8 T-cell epitope (S-510-518) could be detected in nearly all samples of RNA and virus...
Guardat en:
| Publicat a: | J Virol |
|---|---|
| Autors principals: | , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Microbiology (ASM)
1998
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110395/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9621053/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.7.5912-5918.1998 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|