Antiapoptotic Activity of the Herpesvirus Saimiri-Encoded Bcl-2 Homolog: Stabilization of Mitochondria and Inhibition of Caspase-3-Like Activity

Viruses have evolved different strategies to interfere with host cell apoptosis. Herpesvirus saimiri (HVS) and other lymphotropic herpesviruses code for proteins that are homologous to the cellular antiapoptotic Bcl-2. In this study HVS-Bcl-2 was stably expressed in the human leukemia cell line Jurk...

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Bibliographic Details

Published in:	J Virol
Main Authors:	Derfuss, Tobias, Fickenscher, Helmut, Kraft, Michael S., Henning, Golo, Lengenfelder, Doris, Fleckenstein, Bernhard, Meinl, Edgar
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 1998
Subjects:	Virus-Cell Interactions
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110393/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9621051/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.7.5897-5904.1998
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