Transformation of human T-cell clones by Herpesvirus saimiri: intact antigen recognition by autonomously growing myelin basic protein-specific T cells.

Herpesvirus saimiri has recently been shown to immortalize human T cells. It was unknown, however, whether Herpesvirus saimiri transformation affects T-cell receptor (TCR) expression and signal transduction. In the present study, we have transformed CD4+ human T-cell clones specific for human myelin...

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Detalhes bibliográficos
Main Authors: Weber, F, Meinl, E, Drexler, K, Czlonkowska, A, Huber, S, Fickenscher, H, Müller-Fleckenstein, I, Fleckenstein, B, Wekerle, H, Hohlfeld, R
Formato: Artigo
Idioma:Inglês
Publicado em: 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC47919/
https://ncbi.nlm.nih.gov/pubmed/7504291
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