Inhibition of Human Immunodeficiency Virus Rev and Human T-Cell Leukemia Virus Rex Function, but Not Mason-Pfizer Monkey Virus Constitutive Transport Element Activity, by a Mutant Human Nucleoporin Targeted to Crm1

The hypothesis that the cellular protein Crm1 mediates human immunodeficiency virus type 1 (HIV-1) Rev-dependent nuclear export posits that Crm1 can directly interact both with the Rev nuclear export signal (NES) and with cellular nucleoporins. Here, we demonstrate that Crm1 is indeed able to intera...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Bogerd, Hal P., Echarri, Asier, Ross, Ted M., Cullen, Bryan R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Virus-Cell Interactions
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110274/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9765402/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.11.8627-8635.1998
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