Inhibition of Human Immunodeficiency Virus Rev and Human T-Cell Leukemia Virus Rex Function, but Not Mason-Pfizer Monkey Virus Constitutive Transport Element Activity, by a Mutant Human Nucleoporin Targeted to Crm1

The hypothesis that the cellular protein Crm1 mediates human immunodeficiency virus type 1 (HIV-1) Rev-dependent nuclear export posits that Crm1 can directly interact both with the Rev nuclear export signal (NES) and with cellular nucleoporins. Here, we demonstrate that Crm1 is indeed able to intera...

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Pubblicato in:	J Virol
Autori principali:	Bogerd, Hal P., Echarri, Asier, Ross, Ted M., Cullen, Bryan R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Virus-Cell Interactions
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110274/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9765402/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.11.8627-8635.1998
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