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Activation of the Mason–Pfizer monkey virus protease within immature capsids in vitro

For all retroviruses, the completion of the viral budding process correlates with the activation of the viral protease by an unknown mechanism, and, as the structural (Gag) polyproteins are cleaved by the viral protease, maturation of the immature virus-like particle into an infectious virion. Unlik...

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Bibliographic Details
Main Authors: Parker, Scott D., Hunter, Eric
Format: Artigo
Language:Inglês
Published: The National Academy of Sciences 2001
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC64733/
https://ncbi.nlm.nih.gov/pubmed/11724937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.251460998
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