Characterization of Wild-Type Adeno-Associated Virus Type 2-Like Particles Generated during Recombinant Viral Vector Production and Strategies for Their Elimination

The pSub201-pAAV/Ad plasmid cotransfection system was developed to eliminate homologous recombination which leads to generation of the wild-type (wt) adeno-associated virus type 2 (AAV) during recombinant vector production. The extent of contamination with wt AAV has been documented to range between...

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Dades bibliogràfiques

Publicat a:	J Virol
Autors principals:	Wang, Xu-Shan, Khuntirat, Benjawan, Qing, Keyun, Ponnazhagan, Selvarangan, Kube, Dagmar M., Zhou, Shangzhen, Dwarki, Varavani J., Srivastava, Arun
Format:	Artigo
Idioma:	Inglês
Publicat:	American Society for Microbiology (ASM) 1998
Matèries:	Gene Therapy
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110186/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9621003/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.7.5472-5480.1998
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