A Novel Polymorphism at Codon 333 of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Can Facilitate Dual Resistance to Zidovudine and l-2′,3′-Dideoxy-3′-Thiacytidine

Recent clinical trials examining 3′-azido-3′-deoxythymidine (AZT, zidovudine, or Retrovir) combined with l-2′,3′-dideoxy-3′-thiacytidine (3TC or lamivudine) have shown that combination therapy with these nucleoside analogs affords significant virological and clinical benefits. The addition of 3TC to...

Descrición completa

Detalles Bibliográficos

Publicado en:	J Virol
Principais autores:	Kemp, Sharon D., Shi, Chaofu, Bloor, Stuart, Harrigan, P. Richard, Mellors, John W., Larder, Brendan A.
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology (ASM) 1998
Assuntos:	Animal Viruses
Acceso en liña:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110074/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573280/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.6.5093-5098.1998
Tags:	Engadir etiqueta Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!