Identification of Nitric Oxide Synthase 2 as an Innate Resistance Locus against Ectromelia Virus Infection

To assess whether nitric oxide synthase 2 (NOS2) fulfills the criteria of an innate resistance locus against an acute viral infection, we inoculated genetically deficient NOS2−/− mice with virulent ectromelia virus (EV), the causative agent of mousepox. NOS2−/− mice proved highly susceptible to EV y...

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Detalles Bibliográficos

Publicado en:	J Virol
Autores principales:	Karupiah, Gunasegaran, Chen, Jian-He, Nathan, Carl F., Mahalingam, Surendran, MacMicking, John D.
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	American Society for Microbiology (ASM) 1998
Materias:	Viral Pathogenesis and Immunity
Acceso en línea:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110049/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9696880/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.9.7703-7706.1998
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