Stabilization of Human Immunodeficiency Virus Type 1 Envelope Glycoprotein Trimers by Disulfide Bonds Introduced into the gp41 Glycoprotein Ectodomain

Biochemical and structural studies of fragments of the ectodomain of the human immunodeficiency virus type 1 (HIV-1) gp41 transmembrane envelope glycoprotein have demonstrated that the molecular contacts between alpha helices allow the formation of a trimeric coiled coil. By introducing cysteine res...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Farzan, Michael, Choe, Hyeryun, Desjardins, Elizabeth, Sun, Ying, Kuhn, Jens, Cao, Jie, Archambault, Danielle, Kolchinsky, Peter, Koch, Markus, Wyatt, Richard, Sodroski, Joseph
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Animal Viruses
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC110020/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9696864/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.9.7620-7625.1998
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