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Mutations in the Human Immunodeficiency Virus Type 1 Integrase D,D(35)E Motif Do Not Eliminate Provirus Formation

The core domain of human immunodeficiency virus type 1 (HIV-1) integrase (IN) contains a D,D(35)E motif, named for the phylogenetically conserved glutamic acid and aspartic acid residues and the invariant 35 amino acid spacing between the second and third acidic residues. Each acidic residue of the...

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Autors principals: Gaur, Meenakshi, Leavitt, Andrew D.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC109991/
https://ncbi.nlm.nih.gov/pubmed/9573231
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