Antibody-Mediated Neutralization of Human Rhinovirus 14 Explored by Means of Cryoelectron Microscopy and X-Ray Crystallography of Virus-Fab Complexes

The structures of three different human rhinovirus 14 (HRV14)-Fab complexes have been explored with X-ray crystallography and cryoelectron microscopy procedures. All three antibodies bind to the NIm-IA site of HRV14, which is the β-B–β-C loop of the viral capsid protein VP1. Two antibodies, Fab17-IA...

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Autors principals: Che, Zhiwei, Olson, Norman H., Leippe, Donna, Lee, Wai-ming, Mosser, Anne G., Rueckert, Roland R., Baker, Timothy S., Smith, Thomas J.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 1998
Matèries:
Animal Viruses
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC109976/
https://ncbi.nlm.nih.gov/pubmed/9573224
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