Antibody-Mediated Neutralization of Human Rhinovirus 14 Explored by Means of Cryoelectron Microscopy and X-Ray Crystallography of Virus-Fab Complexes

The structures of three different human rhinovirus 14 (HRV14)-Fab complexes have been explored with X-ray crystallography and cryoelectron microscopy procedures. All three antibodies bind to the NIm-IA site of HRV14, which is the β-B–β-C loop of the viral capsid protein VP1. Two antibodies, Fab17-IA...

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Publié dans:	J Virol
Auteurs principaux:	Che, Zhiwei, Olson, Norman H., Leippe, Donna, Lee, Wai-ming, Mosser, Anne G., Rueckert, Roland R., Baker, Timothy S., Smith, Thomas J.
Format:	Artigo
Langue:	Inglês
Publié:	American Society for Microbiology (ASM) 1998
Sujets:	Animal Viruses
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109976/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9573224/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.6.4610-4622.1998
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