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The Early Region 4 orf4 Protein of Human Adenovirus Type 5 Induces p53-Independent Cell Death by Apoptosis

Previous studies by our group showed that infection of human and rodent cells by human adenovirus type 5 (Ad5) results in the induction of p53-independent apoptosis and cell death that are dependent upon transactivation of early region 4 (E4). To identify which E4 products are involved, studies were...

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Bibliographic Details
Main Authors: Marcellus, Richard C., Lavoie, Josée N., Boivin, Dominique, Shore, Gordon C., Ketner, Gary, Branton, Philip E.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 1998
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC109936/
https://ncbi.nlm.nih.gov/pubmed/9696808
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