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Circumvention of Immunity to the Adenovirus Major Coat Protein Hexon

Immunity to adenoviruses is an important hurdle to be overcome for successful gene therapy. The presence of antibodies to the capsid proteins prevents efficacious adenovirus vector administration in vivo. We tested whether immunity to a particular serotype of adenovirus (Ad5) may be overcome with a...

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Detaylı Bibliyografya
Asıl Yazarlar: Roy, Soumitra, Shirley, Pamela S., McClelland, Alan, Kaleko, Michael
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 1998
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC109897/
https://ncbi.nlm.nih.gov/pubmed/9658137
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