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Circumvention of Immunity to the Adenovirus Major Coat Protein Hexon

Immunity to adenoviruses is an important hurdle to be overcome for successful gene therapy. The presence of antibodies to the capsid proteins prevents efficacious adenovirus vector administration in vivo. We tested whether immunity to a particular serotype of adenovirus (Ad5) may be overcome with a...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Roy, Soumitra, Shirley, Pamela S., McClelland, Alan, Kaleko, Michael
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 1998
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC109897/
https://ncbi.nlm.nih.gov/pubmed/9658137
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