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Circumvention of Immunity to the Adenovirus Major Coat Protein Hexon

Immunity to adenoviruses is an important hurdle to be overcome for successful gene therapy. The presence of antibodies to the capsid proteins prevents efficacious adenovirus vector administration in vivo. We tested whether immunity to a particular serotype of adenovirus (Ad5) may be overcome with a...

詳細記述

保存先:
書誌詳細
出版年:J Virol
主要な著者: Roy, Soumitra, Shirley, Pamela S., McClelland, Alan, Kaleko, Michael
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology (ASM) 1998
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109897/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9658137/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.8.6875-6879.1998
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