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Naturally Occurring Mutations Define a Novel Function of the Hepatitis B Virus Core Promoter in Core Protein Expression

Functional analysis of naturally occurring hepatitis B virus (HBV) mutations is crucial in understanding their impact on disease. We have recently identified two mutations in the HBV core promoter of an HBV strain associated with fulminant hepatitis leading to highly (15-fold) enhanced replication a...

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Détails bibliographiques
Publié dans:J Virol
Auteurs principaux: Baumert, Thomas F., Marrone, Aldo, Vergalla, John, Liang, T. Jake
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology (ASM) 1998
Sujets:
Accès en ligne:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109887/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9658127/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.8.6785-6795.1998
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