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Naturally Occurring Mutations Define a Novel Function of the Hepatitis B Virus Core Promoter in Core Protein Expression

Functional analysis of naturally occurring hepatitis B virus (HBV) mutations is crucial in understanding their impact on disease. We have recently identified two mutations in the HBV core promoter of an HBV strain associated with fulminant hepatitis leading to highly (15-fold) enhanced replication a...

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Bibliographic Details
Published in:J Virol
Main Authors: Baumert, Thomas F., Marrone, Aldo, Vergalla, John, Liang, T. Jake
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 1998
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109887/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9658127/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.8.6785-6795.1998
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