Human Thymidine Kinase Can Functionally Replace Herpes Simplex Virus Type 1 Thymidine Kinase for Viral Replication in Mouse Sensory Ganglia and Reactivation from Latency upon Explant

Herpes simplex virus type 1 thymidine kinase exhibits a strikingly broad substrate specificity. It is capable of phosphorylating deoxythymidine and deoxyuridine as does human thymidine kinase, deoxycytidine as does human deoxycytidine kinase, the cytosolic kinase whose amino acid sequence it most cl...

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Pubblicato in:	J Virol
Autori principali:	Chen, Shun-Hua, Cook, W. James, Grove, Kristie L., Coen, Donald M.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology (ASM) 1998
Soggetti:	Viral Pathogenesis and Immunity
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109874/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9658118/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.8.6710-6715.1998
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