Rotavirus 2/6 Viruslike Particles Administered Intranasally with Cholera Toxin, Escherichia coli Heat-Labile Toxin (LT), and LT-R192G Induce Protection from Rotavirus Challenge

We have shown that rotavirus 2/6 viruslike particles composed of proteins VP2 and VP6 (2/6-VLPs) administered to mice intranasally with cholera toxin (CT) induced protection from rotavirus challenge, as measured by virus shedding. Since it is unclear if CT will be approved for human use, we evaluate...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	O’Neal, Christine M., Clements, John D., Estes, Mary K., Conner, Margaret E.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Viral Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109829/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9525668/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.4.3390-3393.1998
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