Protective Immunity and Antibody-Secreting Cell Responses Elicited by Combined Oral Attenuated Wa Human Rotavirus and Intranasal Wa 2/6-VLPs with Mutant Escherichia coli Heat-Labile Toxin in Gnotobiotic Pigs

Two combined rotavirus vaccination regimens were evaluated in a gnotobiotic pig model of rotavirus infection and disease and were compared to previously tested rotavirus vaccination regimens. The first (AttHRV/VLP2×) involved oral inoculation with one dose of attenuated (Att) Wa human rotavirus (HRV...

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Detalhes bibliográficos
Main Authors: Yuan, Lijuan, Iosef, Cristiana, Azevedo, Marli S. P., Kim, Yunjeong, Qian, Yuan, Geyer, Annelise, Nguyen, Trang Van, Chang, Kyeong-Ok, Saif, Linda J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2001
Assuntos:
Vaccines and Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC114490/
https://ncbi.nlm.nih.gov/pubmed/11533185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.75.19.9229-9238.2001
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