Recombinant Respiratory Syncytial Virus (RSV) Bearing a Set of Mutations from Cold-Passaged RSV Is Attenuated in Chimpanzees

A set of five missense mutations previously identified by nucleotide sequence analysis of subgroup A cold-passaged (cp) respiratory syncytial virus (RSV) has been introduced into a recombinant wild-type strain of RSV. This recombinant virus, designated rA2cp, appears to replicate less efficiently in...

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Detalhes bibliográficos

Publicado no:	J Virol
Principais autores:	Whitehead, Stephen S., Juhasz, Katalin, Firestone, Cai-Yen, Collins, Peter L., Murphy, Brian R.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	American Society for Microbiology (ASM) 1998
Assuntos:	Viral Pathogenesis and Immunity
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC109683/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9557743/ https://ncbi.nlm.nih.govhttps://doi.org/10.1128/jvi.72.5.4467-4471.1998
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