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Recombinant Respiratory Syncytial Virus (RSV) Bearing a Set of Mutations from Cold-Passaged RSV Is Attenuated in Chimpanzees

A set of five missense mutations previously identified by nucleotide sequence analysis of subgroup A cold-passaged (cp) respiratory syncytial virus (RSV) has been introduced into a recombinant wild-type strain of RSV. This recombinant virus, designated rA2cp, appears to replicate less efficiently in...

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Detaylı Bibliyografya
Asıl Yazarlar: Whitehead, Stephen S., Juhasz, Katalin, Firestone, Cai-Yen, Collins, Peter L., Murphy, Brian R.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Microbiology 1998
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC109683/
https://ncbi.nlm.nih.gov/pubmed/9557743
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