Effectiveness of Postinoculation (R)-9-(2-Phosphonylmethoxypropyl)Adenine Treatment for Prevention of Persistent Simian Immunodeficiency Virus SIV(mne) Infection Depends Critically on Timing of Initiation and Duration of Treatment

(R)-9-(2-Phosphonylmethoxypropyl)adenine (PMPA), an acyclic nucleoside phosphonate analog, is one of a new class of potent antiretroviral agents. Previously, we showed that PMPA treatment for 28 days prevented establishment of persistent simian immunodeficiency virus (SIV) infection in macaques even...

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Auteurs principaux: Tsai, Che-Chung, Emau, Peter, Follis, Kathryn E., Beck, Thomas W., Benveniste, Raoul E., Bischofberger, Norbert, Lifson, Jeffrey D., Morton, William R.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 1998
Sujets:
Animal Viruses
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC109656/
https://ncbi.nlm.nih.gov/pubmed/9557716
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