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Mutational Scan of the Human Immunodeficiency Virus Type 2 Integrase Protein

Retroviral integrase (IN) cleaves linear viral DNA specifically near the ends of the DNA (cleavage reaction) and subsequently couples the processed ends to phosphates in the target DNA (integration reaction). In vitro, IN catalyzes the disintegration reaction, which is the reverse of the integration...

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Autori principali: van den Ent, Fusinita M. I., Vos, Arnold, Plasterk, Ronald H. A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 1998
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC109617/
https://ncbi.nlm.nih.gov/pubmed/9557677
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